Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

OWL--a non-redundant composite protein sequence database

A J Bleasby1, D Akrigg, T K Attwood

  • 1DRAL, Warrington, Cheshire, UK.

Nucleic Acids Research
|September 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

ELIXIR-UK role in bioinformatics training at the national level and across ELIXIR.

F1000Research·2017
Same author

Stability and solubility engineering of the EphB4 tyrosine kinase catalytic domain using a rationally designed synthetic library.

Protein engineering, design & selection : PEDS·2013
Same author

Utopia documents: linking scholarly literature with research data.

Bioinformatics (Oxford, England)·2010
Same author

WIWS: a protein structure bioinformatics Web service collection.

Nucleic acids research·2010
Same author

UTOPIA-User-Friendly Tools for Operating Informatics Applications.

Comparative and functional genomics·2008
Same author

METIS: multiple extraction techniques for informative sentences.

Bioinformatics (Oxford, England)·2005
Same journal

Correction to 'scSuperAnnotator: A platform for benchmarking comparison and visualizing automated cellular annotation methods for scRNA-seq data'.

Nucleic acids research·2026
Same journal

Correction to 'Differentiable partition function calculation for RNA'.

Nucleic acids research·2026
Same journal

Deployment of non-canonical splicing in tunicate genomes is mediated by divergent U2AF function and changing m6A modification in U1 and U6 snRNA.

Nucleic acids research·2026
Same journal

Bacillus subtilis DnaB forms multiple protein-protein interactions essential for DNA replication initiation.

Nucleic acids research·2026
Same journal

Multiple forms of protein-protein and DNA binding are exhibited by BrxC from the BREX phage restriction system.

Nucleic acids research·2026
Same journal

Biosynthesis of glycosylated 5-hydroxycytosine in the DNA of diverse viruses.

Nucleic acids research·2026
See all related articles

A new protein sequence database called OWL offers a comprehensive, non-redundant collection of biological data. This integrated resource is regularly updated and includes tools for efficient sequence analysis and retrieval.

Area of Science:

  • Bioinformatics
  • Molecular Biology
  • Computational Biology

Background:

  • Protein sequence data is fundamental to understanding biological functions.
  • Existing databases often contain redundant information, complicating analysis.
  • A need exists for a curated, non-redundant protein sequence resource.

Purpose of the Study:

  • To describe the creation and features of the OWL protein sequence database.
  • To provide a comprehensive and non-redundant protein sequence resource.
  • To offer integrated software tools for database exploration and analysis.

Main Methods:

  • Amalgamation of data from six primary public sources.
  • Application of strict redundancy criteria for data curation.
  • Monthly updates to ensure data currency and comprehensiveness.

Related Experiment Videos

Main Results:

  • Creation of the OWL (Open-ended, Weakly-linked) database.
  • The database currently contains over 76,000 non-redundant protein sequence entries.
  • Significant growth, an eight-fold increase in size over six years.

Conclusions:

  • OWL serves as a valuable, integrated resource for protein sequence data.
  • The database facilitates efficient information retrieval and sequence analysis.
  • Regular updates and redundancy control enhance its utility for researchers.