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Heparin-induced thrombocytopenia and thrombosis: a case study and clinical overview
D M Lapka1, L D Wild, L A Barbour
1Division of Surgical Oncology, University of Illinois, Chicago Specialized Cancer Center.
Purpose/Objectives:
To describe the mechanisms and nursing care associated with heparin-induced thrombocytopenia and thrombosis (HITT).
Data Sources:
Published books and journal articles as well as clinical experience.
Data Synthesis:
HITT is an immune reaction that occurs in 1%-10% of individuals receiving heparin therapy. Characterized by a sudden drop in platelets, it can result in life-threatening hemorrhage and thrombus-related events.
Conclusions:
Heparin commonly is used in many oncology treatment settings. Awareness of this potentially serious complication and knowledge of its treatment is critical to safe administration.
Implications For Nursing Practice:
Astute assessment skills are the key to diagnosis and treatment of HITT.