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Gastric pressures in pigs during eating and drinking
1Department of Physiology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853.
Physiology & Behavior
|August 1, 1994
Summary
Gastric pressure changes during eating and drinking reveal that stomach distention plays a lesser role in satiety when food is consumed spontaneously compared to after deprivation.
Area of Science:
- Physiology
- Gastroenterology
Background:
- Gastric pressure dynamics are crucial for understanding satiety regulation.
- The role of gastric distention in satiety requires further investigation.
Purpose of the Study:
- To investigate gastric pressure changes during spontaneous and deprivation-induced eating and drinking in pigs.
- To assess the contribution of gastric distention to satiety under different feeding conditions.
Main Methods:
- Miniature pressure transducers were implanted in the gastric lumen of six young pigs.
- Gastric pressures were recorded during spontaneous eating/drinking and after periods of food/water deprivation.
Main Results:
- Spontaneous eating/drinking maintained higher intermeal gastric pressures (22-25 cm H2O) compared to post-deprivation.
- Eating after deprivation increased gastric pressure from 9 to 22 cm H2O, while drinking caused a smaller rise to 13 cm H2O.
- During spontaneous intake, gastric pressure rose only to preingestive levels, suggesting a reduced role for distention in satiety.
Conclusions:
- Gastric distention plays a less direct role in satiety during spontaneous eating and drinking.
- Satiety mechanisms may differ significantly between spontaneous feeding and feeding after a period of deprivation.