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[Hepatorenal insufficiency syndrome in endotoxic shock (a light optical and electron microscopic study)]
Anesteziologiia I Reanimatologiia
|March 1, 1993
Abstract:
Experimental endotoxemia in the liver and kidneys was characterized by initial hemodynamic and rheologic disorders as well as intravascular coagulation disturbances some hours later. Hypoperfusion of these organs resulted in dystrophic changes in hepatocytes. Progression of endotoxin shock was accompanied by irreversible cellular changes. Late endotoxemia was characterized by adaptive changes associated with the improvement of microcirculation.