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Related Experiment Videos

Hemodynamic analysis could resolve the pulsatile blood flow controversy

G Wright1

  • 1Department of Biomedical Engineering and Medical Physics, University of Keele, Staffordshire, England.

The Annals of Thoracic Surgery
|October 1, 1994
PubMed
Summary

Pulsatile cardiopulmonary bypass popularity fluctuates due to misunderstandings of its mechanical properties. A new analysis using hemodynamic power and impedance parameters is needed for accurate assessment.

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Area of Science:

  • Cardiovascular Physiology
  • Biomedical Engineering
  • Medical Device Technology

Background:

  • Pulsatile cardiopulmonary bypass (CPB) has seen variable adoption.
  • Previous justifications for pulsatile flow relied on physiologic parameters, creating a weak theoretical basis.
  • This led to misunderstandings regarding the fundamental mechanical properties of pulsatile flow.

Purpose of the Study:

  • To discuss reasons for the fluctuating popularity of pulsatile CPB.
  • To highlight the need for a revised theoretical framework for pulsatile flow analysis.
  • To propose analyzing pulsatile blood flow using hemodynamic power and impedance parameters.

Main Methods:

  • Discussion of historical perspectives on pulsatile CPB.
  • Critique of existing theoretical frameworks based on physiologic parameters.

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  • Proposal for a new analytical approach focusing on mechanical properties.

    • Main Results:

    • Identified that reliance on physiologic parameters has led to misunderstandings of pulsatile flow mechanics.
    • Noted that modified roller pumps, despite being termed 'pulsatile,' have limited pulsatile power output compared to the heart.
    • Established the inadequacy of current theoretical models for pulsatile CPB.

    Conclusions:

    • A fresh approach is required to analyze pulsatile blood flow.
    • Hemodynamic power and impedance parameters offer a more robust framework for understanding pulsatile flow.
    • Accurate analysis of mechanical properties is crucial for the appropriate application of pulsatile CPB.