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[Late potentials analysis in patients with malignant ventricular arrhythmia]

J S Lage1, A Hernández Madrid, E Marín-Huerta

  • 1Hospital Ramón y Cajal, Unidad de Arritmias, Madrid, España.

Arquivos Brasileiros De Cardiologia
|February 1, 1994
PubMed
Summary

Late potentials are more common in patients with ventricular tachycardia than fibrillation. Their presence strongly predicts inducible ventricular tachycardia, aiding in risk stratification for sudden cardiac death.

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Area of Science:

  • Cardiology
  • Electrophysiology
  • Cardiac Electrophysiology

Context:

  • Spontaneous ventricular arrhythmias, including ventricular tachycardia (VT) and ventricular fibrillation (VF), pose significant risks.
  • Electrophysiological studies (EPS) are crucial for assessing arrhythmia inducibility.
  • Late potentials (LPs) are potential markers of arrhythmogenic substrate.

Purpose:

  • To evaluate the association between late potentials and spontaneous ventricular arrhythmias.
  • To determine the relationship between LPs, organic heart disease, and arrhythmia inducibility during EPS.
  • To explore the correlation between LPs and left ventricular ejection fraction (LVEF).

Summary:

  • Late potentials were identified in 73% of VT patients versus 17% of VF patients.

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  • In ischemic cardiomyopathy, LPs were present in 68%, with 93% inducible VT.
  • LPs were strongly associated with inducible VT (81.5% sensitivity, 78% specificity) and inversely correlated with LVEF.

    • Impact:

    • Late potentials are more prevalent in VT than VF, suggesting substrate differences.
    • The presence of LPs is a significant predictor of inducible ventricular tachycardia.
    • Findings aid in risk stratification and management of patients with ventricular arrhythmias.