Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Infant formula development: past, present and future

J D Benson1, M L Masor

  • 1Pediatric Research and Development, Ross Products Division, Abbott Laboratories, Columbus, OH 43216.

Endocrine Regulations
|March 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparison of dilute and nondilute osmotic equilibrium models for erythrocytes.

Cryobiology·2022
Same author

The cryobiology of spermatozoa.

Theriogenology·2012
Same author

Papillomavirus E2 induces senescence in HPV-positive cells via pRB- and p21(CIP)-dependent pathways.

The EMBO journal·2000
Same author

Effects of Percoll separation, cryoprotective agents, and temperature on plasma membrane permeability characteristics of murine spermatozoa and their relevance to cryopreservation.

Biology of reproduction·1999
Same author

Hydraulic conductivity (Lp) and its activation energy (Ea), cryoprotectant agent permeability (Ps) and its Ea, and reflection coefficients (sigma) for golden hamster individual pancreatic islet cell membranes.

Cryobiology·1999
Same author

Formula tolerance in postbreastfed and exclusively formula-fed infants.

Pediatrics·1999
Same journal

Early life adversity influences brain development through neuroendocrine, immune, and microbiota-related mechanisms: A review.

Endocrine regulations·2026
Same journal

Endocannabinoid signalling in the regulation of hypothalamic-pituitary neuroendocrine circuits: A review.

Endocrine regulations·2026
Same journal

Current perspectives on the pathogenesis of multiple sclerosis: A minireview.

Endocrine regulations·2026
Same journal

One genotype with a myriad of phenotypes: A family with multiple endocrine neoplasia.

Endocrine regulations·2026
Same journal

Modulation of appetite- and metabolism-regulating hormones after bariatric embolization, sleeve gastrectomy, and gastric plication.

Endocrine regulations·2026
Same journal

Analysis of the risk factors impact on the life quality of patients with arterial hypertension.

Endocrine regulations·2026
See all related articles

Infant formula development requires identifying special nutritional needs and improving composition based on human milk. New formulas must demonstrate clear infant benefits, supported by thorough research, not just compositional changes.

Area of Science:

  • Nutritional Science
  • Pediatrics
  • Biochemistry

Background:

  • Infant formulas cater to healthy infants and those with special needs, such as low-birth-weight, allergies, or metabolic disorders.
  • Formula development is driven by identified infant nutritional requirements and evolving scientific knowledge, exemplified by taurine addition for visual function.
  • Human milk serves as a benchmark for infant formula, though its biological complexity, including living cells and unique molecules, cannot be fully replicated.

Observation:

  • Infant formula must achieve stability for up to 36 months, a constraint not applicable to human milk.
  • Fundamental differences between human milk and infant formula necessitate compositional variations to achieve comparable clinical outcomes.
  • New or modified formulas require demonstrable infant advantages, moving beyond mere compositional alterations.

Related Experiment Videos

Findings:

  • The development of specialized formulas, like soy fiber-containing options for post-diarrhea refeeding, addresses specific infant populations.
  • Continuous updates to existing formulas incorporate new nutritional insights, enhancing their suitability for infant development.
  • Replication of human milk's complex biological components in infant formula remains a significant challenge due to inherent differences.

Implications:

  • Future infant formula innovation should prioritize evidence-based advancements conferring clear clinical benefits.
  • Rigorous research and identification of knowledge gaps are crucial before implementing formula modifications or developing new products.
  • The distinct biological nature of human milk and the shelf-life requirements of infant formula necessitate distinct approaches to formulation for optimal infant health outcomes.