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Psoriasis and eczema are not mutually exclusive diseases
1St. John's Institute of Dermatology, St. Thomas' Hospital, London, UK.
Dermatology (Basel, Switzerland)
|January 1, 1994
Summary
This study found that eczema and psoriasis can occur together in individuals. This challenges previous beliefs and suggests shared pathological mechanisms may be involved in these common skin conditions.
Area of Science:
- Dermatology
- Epidemiology
- Pediatric Health
Background:
- Previous reports suggested limited co-occurrence of psoriasis and eczema.
- Understanding disease co-occurrence may reveal shared or opposing pathological mechanisms.
Purpose of the Study:
- To investigate the simultaneous and consecutive occurrence of eczema and psoriasis in individuals.
- To assess the co-occurrence of these two common skin conditions.
Main Methods:
- Analysis of skin examination data from 9,263 British children (National Child Development Survey).
- Data collected on children born between March 3rd-9th, 1958, assessed at ages 11 and 16.
- Statistical analysis focused on the co-occurrence of visible eczema and psoriasis.
Main Results:
- 5 out of 354 children (1.4%) with eczema also had psoriasis.
- 89 out of 8,909 children (1.0%) without eczema had psoriasis.
- The relative risk of psoriasis in children with eczema was 1.41 (95% CI: 0.58–3.46).
Conclusions:
- Contrary to some hospital-based studies, this large population study indicates eczema and psoriasis can co-occur.
- Findings suggest concurrent and consecutive presence of both conditions in individuals.
- The co-occurrence warrants further investigation into shared underlying mechanisms.