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Sclerosing peritonitis

V D Bowers1, J R Ackermann, W Richardson

  • 1University of South Florida, College of Medicine, Department of Surgery, Tampa 33606.

Clinical Transplantation
|August 1, 1994
PubMed
Summary
This summary is machine-generated.

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Sclerosing peritonitis (SP) can progress even after peritoneal dialysis cessation and kidney transplant. This condition may cause mechanical small bowel obstruction in patients with a history of peritoneal dialysis.

Area of Science:

  • Nephrology
  • Gastroenterology
  • Pathology

Background:

  • Sclerosing peritonitis (SP) is a rare condition affecting the abdominal lining, with unclear etiology and no established preventative treatments.
  • SP has been linked to peritoneal dialysis, certain medications, and prior peritonitis.
  • The fibrotic process in SP involves visceral and parietal peritoneal surfaces.

Observation:

  • This report details three cases where sclerotic peritonitis progressed post-peritoneal dialysis and successful renal transplantation.
  • The progression manifested as a dense, fibrotic encasing peel, distinct from typical postoperative adhesions.
  • This fibrotic tissue led to mechanical small bowel obstruction in all reported cases.

Findings:

  • Sclerosing peritonitis can exhibit continued progression despite the cessation of peritoneal dialysis.

Related Experiment Videos

  • Post-transplant mechanical small bowel obstruction can occur in patients with a history of SP related to peritoneal dialysis.
  • The observed fibrotic tissue in these cases was pathologically distinct from standard postoperative adhesions.

    • Implications:

    • Sclerosing peritonitis should be considered in the differential diagnosis of small bowel obstruction in patients undergoing peritoneal dialysis.
    • Patients with a history of peritoneal dialysis who have undergone renal transplantation should be evaluated for SP if presenting with small bowel obstruction symptoms.
    • Further research into the pathogenesis and management of sclerosing peritonitis is warranted.