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T-cell lymphoma of the tonsil with Ki-1 antigen expression
K Yoshioka1, Y Hirayama, H Andachi
1First Department of Internal Medicine, Matsushita Memorial Hospital, Osaka.
Internal Medicine (Tokyo, Japan)
|July 1, 1994
Abstract:
A 52-year-old woman was admitted to our hospital with a fever and swelling of the tonsils and lymph nodes. A tonsillectomy was performed and she was diagnosed as having non-Hodgkin's lymphoma of T-cell phenotype. Genotypic analysis revealed a rearrangement of the T-cell receptor gene, but not of the immunoglobulin genes. The neoplastic cells of the tonsils also expressed the Ki-1 antigen. The clinical course was aggressive with peripheralization of the neoplastic cells, and the patient died of respiratory failure.