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Evolving a legacy system: restructuring the Mendelian Inheritance in Man database

P Li1, L Kramer, S Pineo

  • 1Johns Hopkins University, Baltimore, MD.

Proceedings. Symposium on Computer Applications in Medical Care
|January 1, 1994
PubMed
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Mendelian Inheritance in Man (MIM) database transitioned to an industry-standard, open-systems architecture in 1994. This enhanced data quality, user navigation, and multimedia delivery, while reducing costs and improving adaptability.

Area of Science:

  • Medical Genetics
  • Bioinformatics
  • Database Management

Background:

  • Mendelian Inheritance in Man (MIM) is a long-standing electronic encyclopedia of human genes and genetic disorders.
  • MIM has evolved significantly over 30 years, necessitating updates to its organizational and software structures.

Purpose of the Study:

  • To detail the 1994 transition of the MIM database.
  • To highlight the benefits of the new architecture based on industry standards, open systems, and extensibility.

Main Methods:

  • Implementation of an industry-standard, open systems architecture.
  • Development of an internal format to enforce data consistency.
  • Focus on extensibility to incorporate future technologies.

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Main Results:

  • Improved user navigation to external genomic databases.
  • Enabled delivery of multimedia information within the database.
  • Enhanced data quality and administrative efficiency.
  • Reduced software maintenance costs and improved content migration.

Conclusions:

  • The 1994 MIM database transition successfully modernized the resource.
  • The new architecture provides a robust, adaptable platform for medical genetics information.
  • The changes ensure MIM's continued relevance and integration with emerging technologies.