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Effects of endotoxin and cytokines on lipid metabolism
I Hardardóttir1, C Grünfeld, K R Feingold
1Department of Medicine, University of California, San Francisco.
Current Opinion in Lipidology
|June 1, 1994
Abstract:
Endotoxin, via cytokines, induces marked changes in lipid metabolism: serum VLDL increases, whereas the effect on LDL levels varies among species. The increase in VLDL is caused by stimulation of hepatic VLDL secretion or inhibition of clearance, or both. These alterations can be deleterious or beneficial effects.