Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A molecular evolutionary framework for eukaryotic model organisms

A Sidow1, W K Thomas

  • 1Department of Molecular and Cell Biology, University of California, Berkeley 94720-3202.

Current Biology : CB
|July 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Two nematodes (Nematoda: Diplogastridae, Rhabditidae) from the invasive millipede <i>Chamberlinius hualienensis</i> Wang, 1956 (Diplopoda, Paradoxosomatidae) on Hachijojima Island in Japan.

Journal of nematology·2019
Same author

Coexisting cryptic species of the Litoditis marina complex (Nematoda) show differential resource use and have distinct microbiomes with high intraspecific variability.

Molecular ecology·2016
Same author

A critique of Rossberg et al.: Noise obscures the genetic signal of meiobiotal ecospecies in ecogenomic datasets.

Proceedings. Biological sciences·2014
Same author

Differentially expressed genes in aortic smooth muscle cells from atherosclerosis-susceptible and atherosclerosis-resistant pigeons.

Poultry science·2012
Same author

Shifting patterns of natural variation in the nuclear genome of caenorhabditis elegans.

BMC evolutionary biology·2011
Same author

Ultrasequencing of the meiofaunal biosphere: practice, pitfalls and promises.

Molecular ecology·2010
Same journal

Pitch selectivity in ferret auditory cortex.

Current biology : CB·2026
Same journal

A cell size-dependent competition between geometry and polarity governs nuclear and spindle positioning in early embryos.

Current biology : CB·2026
Same journal

Trophic cascades drive sustainability in the agricultural heritage rice-fish coculture system.

Current biology : CB·2026
Same journal

Tracking Satb2-positive retinal ganglion cells in zebrafish unveils developmental functional reorganization.

Current biology : CB·2026
Same journal

RhoGAP54D promotes cell size asymmetry and inhibits pulsatile myosin activity in Drosophila neural stem cells.

Current biology : CB·2026
Same journal

Increased rates of hybridization in swordtails are associated with water pollution.

Current biology : CB·2026
See all related articles

RNA polymerase II aids in understanding eukaryotic evolution. This study reveals evolutionary relationships, showing plants and animals share an ancestor excluding fungi, and places Caenorhabditis elegans early in metazoan divergence.

Area of Science:

  • Molecular Evolution
  • Developmental Biology
  • Cell Biology

Background:

  • Understanding model organism biology requires knowing their phylogenetic position.
  • Major model organisms in developmental and cell biology are examined.
  • Evolutionary relationships of fungi, plants, and animals are considered.

Purpose of the Study:

  • To determine the phylogenetic positions of key model organisms.
  • To establish evolutionary relationships among major eukaryotic groups.
  • To assess RNA polymerase II as a tool for phylogenetic analysis.

Main Methods:

  • Comparative analysis of small subunit ribosomal RNA (18S rRNA).
  • Phylogenetic analysis using sequences of the two largest subunits of RNA polymerase II.

Related Experiment Videos

  • Integration of newly determined and published sequence data.

    • Main Results:

    • RNA polymerase II is effective for resolving early eukaryotic phylogenetic branchings.
    • Plants and animals share a common ancestor, excluding fungi.
    • The lineage of Caenorhabditis elegans diverged earlier from Metazoa than other major animal groups.
    • Deuterostomes are shown to have arisen from within protostomes.

    Conclusions:

    • RNA polymerase II is a suitable molecule for elucidating eukaryotic evolutionary relationships.
    • A robust phylogenetic framework enables predictions about conserved biological mechanisms across species.
    • Insights from model organisms can be extended to other biological disciplines.