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Doxorubicin and DNA minor groove-binding oligopeptide conjugates as anticancer agents
1Palo Alto Institute of Molecular Medicine, Mountain View, CA 94043.
Gene
|November 4, 1994
Abstract:
Doxorubicin (Dor) and DNA minor groove-binding oligopeptide conjugates have been synthesized and their antitumor activities tested in vitro against KB cells. These new Dor analogues are less toxic to KB cells than the parent Dor.