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Epidermal growth factor stimulation of lecithin release by human amnion
F Vesce1, C Biondi, M E Ferretti
1Istituto di Clinica Ostetrica e Ginecologica, Università degli Studi di Ferrara, Italia.
Gynecologic and Obstetric Investigation
|January 1, 1994
Abstract:
Lecithin release from human amnion disks was assayed in basal conditions as well as under epidermal growth factor administration. The tissue responded to the peptide by increasing the phospholipid release. A significant effect was observed only after 30 min of treatment. A possible role of epidermal growth factor-induced amniotic lecithin release in fetal lung maturation as well as in the mechanism of delivery is discussed.