Menstrual-related mood changes in patients with oligomenorrhea

In order to evaluate the role of negative anticipation on self-report of premenstrual symptoms, we studied 13 oligomenorrheic and 12 control women with regular menses. Both hormonal and psychological measures (using the Symptom Rating Test) were obtained once a week for 5-9 weeks. The presence of ovulatory cycles was confirmed by progesterone levels > or = 3.0 ng/ml. In both groups, there was a significant increase in the total Symptom Rating Test score during the premenstrual phase with respect to the intermenstrual period. As far as specific symptoms were concerned, MANOVA showed significant premenstrual fluctuations in anxiety, depression, somatic symptoms, and inadequacy in both groups. These results suggest that premenstrual discomfort may be unrelated to both cycle length and negative anticipation of one's menses.