The automated CBC. A current perspective

G L Gulati1, B H Hyun

  • 1Department of Pathology, Jefferson Medical College, Philadelphia, Pennsylvania.

Insights

Complete blood count (CBC) is a blood test profile, not a single test. Its name and included tests have evolved due to automated analyzer capabilities and laboratory variations.

Area of Science:

  • Clinical pathology
  • Hematology

Background:

  • Complete blood count (CBC) is a common laboratory test.
  • Historically, CBC has been referred to by various names such as hemogram and hematology profile.

Purpose of the Study:

  • To clarify the definition and historical nomenclature of the complete blood count.
  • To highlight the evolving nature of the CBC test profile.

Main Methods:

  • Literature review of historical and current terminology for CBC.
  • Analysis of factors influencing the composition of CBC panels.

Main Results:

  • CBC is a profile of multiple tests, not a singular test.
  • Nomenclature has varied, including hemogram, Coulter profile, blood cell profile, and hematology profile.
  • The specific tests within a CBC panel vary by laboratory and analyzer technology.

Conclusions:

  • The term "complete blood count" encompasses a dynamic set of tests.
  • Understanding the variability in CBC nomenclature and composition is crucial for consistent interpretation.