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Eyelid motor abnormalities in progressive supranuclear palsy
Journal of Neural Transmission. Supplementum
|January 1, 1994
Summary
Progressive supranuclear palsy (PSP) frequently causes eyelid motor abnormalities, including blepharospasm and levator inhibition. Understanding these disorders is crucial for diagnosing and managing PSP patients.
Area of Science:
- Neurology
- Ophthalmology
- Movement Disorders
Background:
- Eyelid motor abnormalities are observed in approximately one-third of patients with progressive supranuclear palsy (PSP).
- Ocular and eyelid movements are highly coordinated, particularly in the vertical plane.
- Supranuclear ophthalmoplegia with impaired down gaze is a hallmark of PSP.
Purpose of the Study:
- To review eyelid motor abnormalities in progressive supranuclear palsy.
- To present electrophysiological correlates of specific eyelid disorders in PSP.
Main Methods:
- Review of existing literature on eyelid motor disorders in PSP.
- Presentation of electrophysiological findings related to blepharospasm, levator inhibition, and supranuclear paralysis of lid closure.
Main Results:
- The spectrum of eyelid motor disorders in PSP includes blinking abnormalities, lid retraction, blepharospasm, levator inhibition (blepharokolysis), and supranuclear palsy of lid closure.
- Electrophysiological correlates for these specific eyelid abnormalities are detailed.
Conclusions:
- Disorders of eyelid motility are a significant, though not uncommon, feature of progressive supranuclear palsy.
- Recognizing these eyelid abnormalities aids in the diagnosis and understanding of PSP pathophysiology.