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The Comorosan effect: single- and double-blind studies on the urea/urease system
Physiological Chemistry and Physics
|January 1, 1976
Summary
Irradiation of crystalline substrates with an Hg vapor lamp alters enzymatic reaction rates. New single- and double-blind studies validate this phenomenon, supporting its potential importance in biochemistry.
Area of Science:
- Biochemistry
- Enzymology
- Photochemistry
Background:
- Enzymatic reaction rates can be influenced by external factors.
- Comorosan first reported characteristic alterations in enzymatic rates due to substrate irradiation in 1969.
- The phenomenon involves exposing crystalline substrates to an Hg vapor lamp for specific durations.
Purpose of the Study:
- To investigate and validate the phenomenon of altered enzymatic reaction rates following substrate irradiation.
- To confirm the key features of Comorosan's 1969 findings using rigorous study designs.
Main Methods:
- Utilized single-blind study designs.
- Employed double-blind study designs.
- Involved irradiation of crystalline substrates with an Hg vapor lamp for fixed periods.
Main Results:
- Results from both single- and double-blind studies support the phenomenon.
- The validity of key features of the irradiation-induced enzymatic rate alterations is supported.
- The findings indicate a striking and potentially significant biological effect.
Conclusions:
- The phenomenon of altered enzymatic reaction rates due to substrate irradiation is supported by empirical evidence.
- The study validates Comorosan's initial observations, highlighting its potential significance.
- Further research into this photobiological effect is warranted.