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Neurourologic consequences of accidental intrathecal vincristine: a case report
M R Zaragoza1, M L Ritchey, A Walter
1Department of Surgery, University of Michigan, Ann Arbor.
Medical and Pediatric Oncology
|January 1, 1995
Abstract:
Inadvertent intrathecal administration of vincristine results in severe neurotoxicity. Motor and sensory bladder dysfunction have been reported but the long-term urologic consequences are unknown due to the associated high mortality. We report a case of accidental intrathecal vincristine administration with patient survival and follow-up of 24 months. The child developed a lower motor neuron neuropathic bladder requiring intermittent self-catheterization of the bladder. Urinary tract management of these children should be based on the urodynamic findings.