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[Role of adhesion molecules in interactions of endothelium with leukocytes in inflammatory processes]
D Zapolska-Downar1, A Zapolski-Downar
1Zakład Biochemii Klinicznej i Diagnostyki Laboratoryjnej Pomorskiej Akademii Medycznej, Szczecinie.
Postepy Higieny I Medycyny Doswiadczalnej
|January 1, 1994
Abstract:
This paper reviews recent work regarding the molecules that mediate leukocyte-endothelial cell adhesion, describes the underlying principles of leukocyte migration, and discusses a model of the sequence of events that allows a leukocyte to attach to endothelium and migrate into tissue. Pathophysiological importance of the adhesion molecules in the development of different states of inflammation has been also presented.