Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Choledochal cyst disease. A changing pattern of presentation

P A Lipsett1, H A Pitt, P M Colombani

  • 1Department of Surgery, Johns Hopkins University, Baltimore, Maryland.

Annals of Surgery
|November 1, 1994
PubMed
Summary

Adults and children present choledochal cysts differently, with adults often showing acute biliary or pancreatic symptoms. Surgical excision and reconstruction are safe, effective, and reduce malignancy risk in both groups.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Does preoperative cross-sectional imaging accurately predict main duct involvement in intraductal papillary mucinous neoplasm?

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract·2014
Same author

Severe hepatitis from methyldopa.

Gastroenterology·2012
Same author

Pancreatic enucleation: improved outcomes compared to resection.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract·2012
Same author

Very high serum CA 19-9 levels: a contraindication to pancreaticoduodenectomy?

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract·2009
Same author

Hepatic giant cells in hepatitis C virus (HCV) mono-infection and HCV/HIV co-infection.

Journal of clinical pathology·2008
Same author

Surgical experience with pancreatic and peripancreatic neuroendocrine tumors: Review of 125 patients.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract·2008

Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Hepatobiliary Surgery

Background:

  • Choledochal cysts traditionally present in infants with jaundice, mass, and pain.
  • Recent observations suggest increased recognition of choledochal cysts in adult patients.

Purpose of the Study:

  • To compare the clinical presentation, treatment, and long-term outcomes of choledochal cysts in pediatric versus adult populations.
  • To evaluate the safety and efficacy of surgical management for choledochal cysts across different age groups.

Main Methods:

  • Retrospective review of 42 patients (11 children, 32 adults) treated for choledochal cysts between 1976 and 1993.
  • Data collection included patient presentation, clinical evaluation, operative treatment, and long-term follow-up via records and direct contact.

Related Experiment Videos

Main Results:

  • Children were more likely to exhibit classic symptoms (jaundice, mass, pain) or two of these signs compared to adults.
  • Adults frequently presented with abdominal pain, often misdiagnosed as pancreatitis or acute biliary symptoms requiring cholecystectomy.
  • The most common cyst types were fusiform extrahepatic (Type I) and combined intrahepatic/extrahepatic (Type IVA). Surgical treatment involved cyst excision and hepaticojejunostomy with no operative mortality.
  • Three adults developed malignancy (cholangiocarcinoma or gallbladder cancer); long-term complications included biliary stricture and intrahepatic stones in Type IVA cysts.

Conclusions:

  • Choledochal cyst presentation significantly differs between children and adults, with adults more commonly presenting with acute biliary or pancreatic symptoms.
  • Surgical excision of choledochal cysts combined with biliary bypass (hepaticojejunostomy) is a safe and effective treatment for both children and adults.
  • This surgical approach yields excellent long-term results and effectively minimizes the risk of developing malignancy associated with choledochal cysts.