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Updated: Aug 12, 2026
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The Influence of Liver Resection on Intrahepatic Tumor Growth
Published on: April 9, 2016
Repeat hepatic resections for metastatic colorectal cancer
Y Fong1, L H Blumgart, A Cohen
1Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York.
Annals of Surgery
|November 1, 1994
Summary
Repeat liver resections for colorectal metastases are safe but offer a low chance of cure. Further recurrences are common, suggesting a need for alternative treatments.
Area of Science:
- Hepatobiliary Surgery
- Surgical Oncology
- Colorectal Cancer Metastasis
Background:
- Colorectal cancer frequently metastasizes to the liver.
- Repeat liver resections are considered for isolated liver recurrences.
Purpose of the Study:
- To evaluate the safety and efficacy of repeat liver resections for patients with recurrent colorectal liver metastases.
Main Methods:
- Retrospective review of 25 patients undergoing repeat liver resection for isolated recurrent colorectal metastases.
- Data collected from January 1985 to June 1991 at Memorial Sloan-Kettering Cancer Center.
Main Results:
- No perioperative deaths; 28% complication rate.
- Median survival after second resection was 30 months.
- 20 of 25 patients experienced recurrence within 9 months; no predictive factors identified.
Conclusions:
- Repeat liver resections are safe and improve survival but have a low likelihood of cure.
- High recurrence rates warrant investigation into adjuvant or alternative therapies.
