Related Experiment Videos
Synthesis and hypotensive activity of some heterocyclic analogues of GYKI-12 743
P Mátyus1, E Kasztreiner, E Diesler
1Institute for Drug Research, Budapest, Hungary.
Archiv Der Pharmazie
|September 1, 1994
Abstract:
[1,4]Benzodioxanylmethyl-, [1,4]benzodioxanylmethylaminopropyl- and phenoxyethylaminoethyl-substituted lactams were synthesised and their hypotensive activity was investigated. Some of these compounds show moderate to high hypotensive effect, but they had more toxic and/or side effects than GYKI-12 743.