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Eruptive pseudoangiomatosis: a unique childhood exanthem?
N S Prose1, W Tope, S E Miller
1Department of Medicine (Dermatology), Duke University Medical Center, Durham, NC 27710.
Abstract:
We describe three children with an acute onset and spontaneous resolution of angioma-like papules during an apparent viral illness. A biopsy specimen from one patient revealed a unique histologic appearance that consisted of dilated dermal blood vessels with plump hobnail-shaped endothelial cells. On the basis of the natural history and histopathologic features of this exanthem, we suggest the name eruptive pseudoangiomatosis.
Insights
Three children experienced sudden, resolving angioma-like papules during a viral illness. This condition, termed eruptive pseudoangiomatosis, presents unique vascular changes in the skin.
Area of Science:
- Dermatology
- Pediatrics
- Pathology
Background:
- Viral exanthems are common in children.
- Angioma-like lesions can manifest during infections.
Observation:
- Three children presented with acute onset of angioma-like papules.
- Lesions resolved spontaneously.
- The onset coincided with an apparent viral illness.
Findings:
- Histopathology revealed dilated dermal blood vessels.
- Plump, hobnail-shaped endothelial cells were noted.
- The condition was named eruptive pseudoangiomatosis.
Implications:
- Eruptive pseudoangiomatosis is a distinct clinical and histopathologic entity.
- It is associated with viral infections in children.
- Further research may clarify its pathogenesis and management.