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Premature menopause and low back pain. A population-based study

T Adera1, R A Deyo, R J Donatelle

  • 1Department of Preventive Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814.

Annals of Epidemiology
|September 1, 1994
PubMed
Summary

Premature menopause significantly increases the risk of low back pain in women. Early menopause and longer time since menopause are linked to higher pain prevalence, suggesting a strong association.

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Area of Science:

  • Reproductive Health
  • Musculoskeletal Health
  • Epidemiology

Background:

  • Menopause, the cessation of menstruation, typically occurs naturally between ages 45-55.
  • Premature menopause, occurring before age 40, affects a significant portion of the female population.
  • Low back pain is a prevalent condition with multifactorial causes, impacting quality of life.

Purpose of the Study:

  • To investigate the association between premature menopause and the occurrence of low back pain.
  • To determine if age at menopause and time since menopause influence low back pain prevalence.

Main Methods:

  • Analysis of data from 5325 women in the second National Health and Nutrition Examination Survey.
  • Use of multiple logistic regression to assess the relationship between menopausal status and low back pain, controlling for age.

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  • Examination of trends in low back pain based on age at menopause and years since menopause.

    • Main Results:

    • Postmenopausal women were twice as likely to report low back pain compared to premenopausal women (OR=2.1).
    • A significant positive trend was observed between low back pain and earlier age at menopause (P=0.005).
    • Increased years since menopause correlated with higher odds of low back pain (OR=3.0 for >=15 years).
    • Women experiencing menopause before age 30 had over three times the odds of low back pain (OR=3.2).

    Conclusions:

    • Premature menopause is significantly associated with an increased prevalence of low back pain.
    • Earlier age at menopause and longer duration post-menopause are linked to higher odds of experiencing low back pain.
    • Further research is recommended to elucidate mechanisms and contributing factors to this association.