Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chronic fatigue syndrome--a controlled cross sectional study

A K Rasmussen1, H Nielsen, V Andersen

  • 1Medical Department TTA M. Rigshospitalet, Copenhagen, Denmark.

The Journal of Rheumatology
|August 1, 1994
PubMed
Summary

This study investigated immune system markers in chronic fatigue syndrome (CFS). While some immune differences were observed, the findings do not confirm a direct link between immune system dysfunction and CFS.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Adipokine secretion and lipolysis following gender-affirming treatment in transgender individuals.

Journal of endocrinological investigation·2024
Same author

THE ROMANIAN VERSION OF THE THYROID-RELATED PATIENT-REPORTED OUTCOMES THYPRO AND THYPRO-39. TRANSLATION AND ASSESSMENT OF RELIABILITY AND CROSS-CULTURAL VALIDITY.

Acta endocrinologica (Bucharest, Romania : 2005)·2019
Same author

Posterolateral corner injuries: Epidemiology, anatomy, biomechanics and diagnosis.

Injury·2017
Same author

Internal fixation of femoral neck stress fractures in young female athletes with a dynamic locking plate.

Acta orthopaedica Belgica·2015
Same author

Cytokines in autoimmunity.

Immunology today·2014
Same author

Increased risk of long-term sickness absence, lower rate of return to work, and higher risk of unemployment and disability pensioning for thyroid patients: a Danish register-based cohort study.

The Journal of clinical endocrinology and metabolism·2014

Area of Science:

  • Immunology
  • Chronic Fatigue Syndrome Research

Background:

  • Chronic Fatigue Syndrome (CFS) is a complex condition with unknown etiology.
  • Investigating potential underlying causes like immunodeficiencies or chronic infections is crucial.

Purpose of the Study:

  • To identify signs of immunodeficiencies or longstanding infections in patients with CFS.
  • To compare immune system parameters between CFS patients and healthy controls.

Main Methods:

  • Studied 21 CFS patients and 21 matched controls.
  • Assessed viral antibodies, autoantibody profiles, and immune cell functions (cytokine production, lymphocyte proliferation, NK cell activity, immunoglobulin levels).

Main Results:

  • Significantly higher in vitro production of interleukin-2 and interferon-gamma in CFS patients.

Related Experiment Videos

  • Lower serum IgA and IgE concentrations observed in CFS patients, though this was influenced by higher normal ranges in controls.
  • No other significant differences in immune markers were found between groups.

    • Conclusions:

    • An immune system imbalance in CFS patients cannot be ruled out.
    • The study did not establish a causal relationship between immune system abnormalities and CFS.