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Hypercalcaemia in B cell chronic lymphocytic leukaemia
O Fain1, A el M'Selmi, C Dosquet
1Department of Internal Medicine, Haematology and Pathology, Jean Verdier Hospital, Bondy, France.
British Journal of Haematology
|August 1, 1994
Summary
Hypercalcaemia is uncommon in B cell chronic lymphocytic leukaemia (BCLL). This case study found parathyroid hormone-related protein (PTHrP) mRNA in BCLL tumour samples, explaining the high calcium levels.
Area of Science:
- Oncology
- Endocrinology
- Hematology
Background:
- Hypercalcaemia is a known complication of certain lymphoproliferative disorders like myeloma and T-cell leukemias.
- It is, however, infrequently documented in B cell chronic lymphocytic leukaemia (BCLL).