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Updated: Aug 10, 2026

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice
Published on: January 12, 2017
Dental caries vaccines: science and status
1Indiana University, School of Dentistry, Indianapolis.
Abstract:
Dental caries, caused by the etiologic agent Streptococcus mutans, is considered the most common human infectious disease. Development of a vaccine has been under investigation for more than 25 years. Possible approaches include immunizing patients using an oral vaccine containing components of the causative bacterium and by intramuscular injection. Although both approaches have proved promising, several considerations have delayed further development of a vaccine. This article reviews the scientific results and status of the various vaccines.
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