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[Amebic keratitis-keratitis acanthamoeba]

R Gieryng1, M Prost, H Gieryng

  • 1Katedry Biologii i Parazytologii AM, Lublinie.

Klinika Oczna
|April 1, 1994
PubMed
Summary
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Acanthamoeba keratitis was diagnosed in one patient with corneal ulcers after trauma. The identified Acanthamoeba polyphaga strain showed high virulence in mice, highlighting the need for accurate diagnosis.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Microbiology

Background:

  • Corneal ulcers can have various etiologies, including microbial infections.
  • Bacteriological and mycological examinations are standard for diagnosing corneal ulcers.
  • Parasitological testing is crucial when initial tests are negative.

Observation:

  • Acanthamoeba keratitis was diagnosed in one of seventeen patients with corneal ulcers.
  • The patient had characteristic corneal changes following trauma and was not a contact lens wearer.
  • The causative agent was identified as Acanthamoeba polyphaga (isolate-clone-No. 2961).

Findings:

  • Acanthamoeba polyphaga trophozoites demonstrated low invasiveness but high virulence in BALB/c mice.
  • Direct smears and in vitro culture confirmed the presence and species of the amoeba.

Related Experiment Videos

  • The case highlights a non-contact lens wearer developing Acanthamoeba keratitis.

    • Implications:

    • Accurate laboratory diagnosis is essential for effective Acanthamoeba keratitis management.
    • Discerning interpretation of diagnostic results can prevent unnecessary patient and medical staff anxiety.
    • Understanding Acanthamoeba epidemiology is vital for preventing sight-threatening keratitis.