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Updated: Aug 10, 2026

Ex Vivo Treatment Response of Primary Tumors and/or Associated Metastases for Preclinical and Clinical Development of Therapeutics
Published on: October 2, 2014
[Oncology, pathology and companion animal practice]
1Vakgroepen Pathologie en Ziekten van Gezelschapsdieren, Faculteit der Diergeneeskunde, Universiteit van Utrecht, Nederland.
Abstract:
A review of research in veterinary oncology, as executed in Amsterdam and Utrecht, is presented. Also an inquiry into the cooperation between oncologist, pathologist and practitioner is discussed. It is concluded that microscopic tumour diagnosis is practized at too low a scale (+/- 30%). Veterinary oncology has significance both from the veterinary and the comparative (model) point of view. Etiologic-pathogenetic and biologic-therapeutic aspects are studied in a multidisciplinary way. Intercellular communication, growth factors and intercellular matrix are items of present and future research. Molecular-genetic research is in progress. Prevention of mammary tumours by ovariectomy (dog, cat) and of malignant lymphoma (cat) by fighting FeLV seems promising.

