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Splenectomy for treatment of immunoblastic lymphadenopathy
M Hirose1, R Nakagawa, A Okada
1Department of Paediatrics, Tokushima University School of Medicine, Japan.
British Journal of Haematology
|July 1, 1994
Abstract:
A 5-month-old girl was diagnosed with immunoblastic lymphadenopathy (IBL) on the basis of clinical symptoms and pathological findings. alpha-interferon, immunosuppressive agents such as cyclosporin A, deoxyspagarine, and azathioprine, and an alternating regimen of low-dose 6-mercaptopurine, cyclophosphamide and methotrexate were tried with partial success. Finally, splenectomy was carried out at 58 months of age, inducing prolonged complete remission without any medication.