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Busulfan as a Myelosuppressive Agent for Generating Stable High-level Bone Marrow Chimerism in Mice
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Bone marrow transplantation in Gaucher's disease: effect of mixed chimeric state

K W Chan1, L T Wong, D Applegarth

  • 1Department of Paediatrics, B.C.'s Children's Hospital, Vancouver, Canada.

Bone Marrow Transplantation
|August 1, 1994
PubMed

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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...