[Candida albicans and intestinal involvement]

Area of Science:

• Medical Mycology
• Clinical Microbiology

Background:

• Non-ascosporic yeasts, particularly Candida albicans, are implicated in alvine disorders.
• Accurate laboratory diagnosis is crucial for effective treatment.

Purpose of the Study:

• To compare different culture media for the diagnosis of Candida albicans in fecal samples.
• To determine the significance of non-ascosporic yeasts in alvine disorders.
• To evaluate the efficacy of Nystatin treatment for Candida albicans-associated alvine disorders.

Main Methods:

• Comparison of various culture media for Candida albicans identification.
• Selection of Pagano Levin Base with 2-3-5-triphenyltetrazium chloride and Neomycin as the optimal medium.
• Clinical treatment of patients with confirmed Candida albicans and alvine disorders using Nystatin.

Main Results:

• Candida albicans was the most frequently isolated yeast from patients with alvine disorders.
• The optimized Pagano Levin Base medium demonstrated superior performance for fungal identification.
• Nystatin treatment led to the resolution of alvine disorders and eradication of Candida albicans in most patients.

Conclusions:

• Candida albicans is a significant factor in alvine disorders.
• The optimized Pagano Levin Base medium is highly effective for laboratory diagnosis.
• Nystatin is an effective therapeutic agent for Candida albicans-related alvine disorders.