Controlled trial of three approaches to the treatment of severe malnutrition

S Khanum1, A Ashworth, S R Huttly

  • 1Centre for Human Nutrition, London School of Hygiene and Tropical Medicine, UK.

Lancet (London, England)
|December 24, 1994
PubMed

Insights

Home-based treatment for severely malnourished children is a cost-effective strategy. While it takes longer, this approach is preferred by parents and significantly reduces costs compared to inpatient or day-care options.

Area of Science:

  • Pediatrics
  • Public Health
  • Health Economics

Background:

  • Severe childhood malnutrition poses significant challenges.
  • Domiciliary treatment offers potential economic and practical benefits.
  • Comparing treatment modalities is crucial for optimizing care.

Purpose of the Study:

  • To compare the costs and effectiveness of inpatient, day-care, and home-based treatment for severely malnourished children.
  • To evaluate institutional and parental economic burdens across different treatment settings.
  • To assess parental preference and treatment outcomes.

Main Methods:

  • A controlled trial involving 437 severely malnourished children (aged 12-60 months) in Dhaka.
  • Sequential allocation to inpatient, day-care, or a hybrid home-care model (1 week day-care followed by home care).
  • Comparison of costs (institutional and parental) and time to reach 80% weight-for-height.

Main Results:

  • Home-based care achieved the lowest average cost (1552 taka), significantly less than day-care (2517 taka) and inpatient (6363 taka).
  • Mortality rates were low (<5%) across all groups.
  • The home-based group took longer to recover but was the most popular option, despite higher parental costs due to lack of food supplements.

Conclusions:

  • At-home management of severely malnourished children, following an initial inpatient or day-care period, is a highly cost-effective strategy.
  • This approach balances economic benefits with parental acceptance.
  • Further research into optimizing home-based care delivery, including nutritional support, is warranted.