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Bacteroides fragilis meningitis

C C Ngan1, A L Tan

  • 1Department of Pathology, Singapore General Hospital.

Singapore Medical Journal
|June 1, 1994
PubMed
Summary
This summary is machine-generated.

Bacteroides fragilis, an intestinal bacterium, can cause rare anaerobic meningitis. Prompt diagnosis and anaerobic cultures are crucial, especially with predisposing conditions. Metronidazole effectively treated two reported cases.

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Area of Science:

  • Microbiology
  • Infectious Diseases
  • Neurology

Background:

  • Bacteroides fragilis is a common gut bacterium.
  • Anaerobic bacterial meningitis is a rare but serious infection.
  • Predisposing factors are often associated with anaerobic infections.

Observation:

  • Two cases of anaerobic meningitis caused by Bacteroides fragilis were identified.
  • One case was linked to cholesteotoma, and the other to nasopharyngeal carcinoma.
  • Both patients presented with meningitis.

Findings:

  • Cerebrospinal fluid anaerobic cultures are vital for diagnosing anaerobic meningitis.
  • Early identification of predisposing conditions is essential.
  • Both patients with Bacteroides fragilis meningitis achieved successful outcomes.

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Implications:

  • This study highlights the importance of considering Bacteroides fragilis in anaerobic meningitis cases.
  • It underscores the need for specific diagnostic approaches, including anaerobic cultures.
  • Metronidazole is confirmed as an effective treatment for this rare condition.