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Updated: Jul 24, 2026

Generation and Culturing of Primary Human Keratinocytes from Adult Skin
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Generation and Culturing of Primary Human Keratinocytes from Adult Skin

Published on: December 22, 2017

Preliminary report of the clinical use of cultured allogeneic keratinocytes

S F Malakhov1, B A Paramonov, A V Vasiliev

  • 1Military Medical Academy, St Petersburg, Russia.

Burns : Journal of the International Society for Burn Injuries
|October 1, 1994
PubMed

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Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...