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Post-penetrating keratoplasty glaucoma

G C Sekhar¹, P Vyas, R Nagarajan

¹VST Centre For Glaucoma Care, L.V. Prasad Eye Institute, Hyderabad.

Indian Journal of Ophthalmology

|December 1, 1993

Summary

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Aphakia, pseudophakia, preexisting glaucoma, and regrafting are significant risk factors for developing glaucoma after penetrating keratoplasty. These findings aid in managing patients undergoing corneal transplantation.

Area of Science:

Ophthalmology
Corneal Surgery
Glaucoma Research

Background:

Penetrating keratoplasty (corneal transplant) is a common procedure.
Glaucoma is a potential complication following corneal transplantation.
Identifying risk factors is crucial for patient management.

Purpose of the Study:

To investigate the risk factors associated with the development of glaucoma after penetrating keratoplasty.
To analyze patient data retrospectively to determine predictors of post-keratoplasty glaucoma.

Main Methods:

Retrospective analysis of 190 eyes from 185 patients who underwent penetrating keratoplasty in 1990.
Data collected included patient status (phakia, aphakia, pseudophakia), preexisting glaucoma, and regrafting.
Mean follow-up period was 14.5 months.

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Main Results:

27.4% (52 of 190 eyes) developed new-onset or worsening glaucoma.
Significant risk factors identified: aphakia (37%), pseudophakia (24%), preexisting glaucoma (81.8%), and regrafting (43.18%).
Medical management was used for 38 eyes, and 14 required surgical intervention.

Conclusions:

Aphakia, pseudophakia, preexisting glaucoma, and regrafting are significant risk factors for post-keratoplasty glaucoma.
These factors should be considered in the preoperative assessment and postoperative monitoring of patients.
Further research may explore preventative strategies for high-risk individuals.