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Prospecting for drugs in ancient texts
1Department of Preventive Medicine and Community Health, New Jersey Medical School, Newark 07103.
Nature
|June 30, 1994
Summary
Revisiting traditional plant remedies from historical texts is more cost-effective and potentially more fruitful than mass plant screening for novel drug discovery.
Area of Science:
- Ethnobotany
- Pharmacognosy
- Drug Discovery
Background:
- Current methods for discovering new drugs from plants are expensive and inefficient.
- Mass screening of plant species yields limited success relative to cost.
Purpose of the Study:
- To propose a more economical and productive approach to discovering novel therapeutics.
- To highlight the value of ethnobotanical and historical data in drug discovery.
Main Methods:
- Review of historical and medieval texts documenting plant-based remedies.
- Comparative analysis of traditional knowledge versus modern drug discovery pipelines.
Main Results:
- Historical texts contain extensive information on plant uses for medicinal purposes.
- Re-evaluation of documented traditional remedies offers a promising avenue for identifying new drug leads.
Conclusions:
- Historical ethnobotanical data represents a valuable, underutilized resource for drug discovery.
- Prioritizing research on traditional plant-based medicines can improve the efficiency and reduce the cost of developing new pharmaceuticals.