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Hepatic adenoma: MR characteristics and correlation with pathologic findings
E K Paulson1, J S McClellan, K Washington
1Department of Radiology, Duke University Medical Center, Durham, NC 27710.
AJR. American Journal of Roentgenology
|July 1, 1994
Summary
Hepatic adenomas often appear hyperintense on MRI scans, with this characteristic frequently linked to higher fat content. This study correlates MR imaging features with pathology for better diagnosis.
Area of Science:
- Radiology
- Hepatology
- Oncology
Background:
- Hepatic adenomas are benign liver tumors.
- Accurate diagnosis is crucial for management.
- Magnetic Resonance (MR) imaging is a key diagnostic tool.
Purpose of the Study:
- To characterize the MR appearance of hepatic adenomas.
- To correlate MR imaging findings with histopathologic results.
Main Methods:
- MR examinations of 66 hepatic adenomas in 14 patients were reviewed.
- T1- and T2-weighted spin-echo images were analyzed for signal intensity, pattern, capsule, and hemorrhage.
- Histopathologic specimens from 22 lesions were assessed for fat content, capsule, and hemorrhage.
Main Results:
- Most hepatic adenomas (77% on T1, 74% on T2) were hyperintense relative to liver.
- The majority of lesions (92%) showed a heterogeneous signal pattern.
- Increased fat content (grade 2 or 3) correlated with T1 hyperintensity in 15 of 17 pathologically reviewed lesions.
Conclusions:
- Hepatic adenomas exhibit variable MR imaging appearances.
- Hyperintensity on T1- and T2-weighted images is common.
- Increased lesion fat content is a frequent cause of high signal intensity on MR imaging.