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Orbital and optic pathway sarcoidosis: MR findings
R F Carmody1, M F Mafee, J A Goodwin
1University of Arizona Medical Center, Tucson 85724.
AJNR. American Journal of Neuroradiology
|April 1, 1994
Summary
Magnetic resonance (MR) imaging can reveal sarcoidosis in the orbit and visual pathways. Key findings include optic nerve involvement and abnormalities resembling multiple sclerosis.
Area of Science:
- Neurology
- Radiology
- Ophthalmology
Background:
- Sarcoidosis is a multisystem inflammatory disease.
- Orbital and visual pathway involvement can occur but is less common.
- Accurate diagnosis relies on characteristic imaging findings.
Purpose of the Study:
- To identify and characterize magnetic resonance (MR) findings of sarcoidosis affecting the orbit and visual pathways.
- To differentiate sarcoidosis from other conditions with similar imaging presentations.
Main Methods:
- Retrospective review of MR scans from 15 patients.
- Inclusion of patients with presumed or proven orbital or optic pathway sarcoidosis.
Main Results:
- Optic nerve involvement (granuloma, enhancement, enlargement) was observed in 8 patients.
- Chiasmal involvement occurred in 9 patients; optic radiations showed abnormalities in 1.
- Orbital masses and periventricular white matter lesions mimicked other neurological conditions.
Conclusions:
- MR imaging findings of sarcoidosis in the orbit and visual pathways are diverse.
- Sarcoidosis should be considered in the differential diagnosis of optic nerve/sheath enhancement.
- Orbital sarcoidosis imaging characteristics can resemble pseudotumor.