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Pulmonary autograft in children: realized growth potential
R C Elkins1, C J Knott-Craig, K E Ward
1Department of Surgery, University of Oklahoma Health Sciences Center, Oklahoma City 73190.
Insights
Pulmonary autografts in children show excellent long-term survival and freedom from reoperation. The inclusion cylinder technique for aortic valve replacement appears most promising for optimal growth and durability.
Area of Science:
- Cardiovascular Surgery
- Pediatric Cardiology
- Thoracic Surgery
Background:
- Pulmonary autograft aortic valve replacement offers potential for growth in pediatric patients.
- Assessing long-term aortic root and valve dimensions is crucial for pediatric cardiac surgery outcomes.
Purpose of the Study:
- To compare early and late postoperative aortic annulus and sinotubular dimensions after pulmonary autograft aortic valve replacement in children.
- To evaluate the growth potential and durability of pulmonary autografts in pediatric aortic valve surgery.
Main Methods:
- Retrospective analysis of 86 children (0.9-21 years) undergoing aortic valve replacement with pulmonary autografts between 1986 and 1993.
- Categorization into root replacement (42), inclusion cylinder (24), and scalloped subcoronary implant (20) groups.
- Comparison of aortic annulus and sinotubular junction diameters with normal values predicted by body surface area.
Main Results:
- Actuarial survival at 7 years was 96.5%. Freedom from reoperation was 92% overall.
- The inclusion cylinder technique showed 100% freedom from autograft reoperation.
- Intraaortic implants demonstrated proportional annulus growth, while root replacements showed dilation; sinotubular junctions generally normalized over time.
Conclusions:
- Pulmonary autografts demonstrate favorable long-term survival and durability in pediatric aortic valve replacement.
- The inclusion cylinder technique may offer superior outcomes regarding autograft growth and reduced reoperation rates.
- Monitoring aortic dimensions is essential to understand graft adaptation and potential complications.
Abstract:
Pulmonary autograft replacement of the aortic valve has the potential to remain viable and grow in proportion to the somatic growth of the child. Changes in aortic annulus and sinotubular dimensions were compared early and late postoperatively, and related to normal. Eighty-six children, 0.9 to 21 years, were operated on between 1986 and 1993: 42 had a root replacement, 24 an inclusion cylinder, and 20 a scalloped subcoronary implant. Actuarial survival at 7 years was 96.5% +/- 2.0%. Freedom from reoperation for the pulmonary autograft or the homograft reconstruction of the right ventricular outflow tract was 92% +/- 4%. Freedom from reoperation on the autograft in root replacements was 96% +/- 4%, in the inclusion cylinder was 100%, and in the scalloped subcoronary was 90% +/- 7% (not significant). Aortic annulus and sinotubular junction diameters were compared with normal values predicted by body surface area. In 22 intraaortic implants, early and late postoperative annulus diameter mean Z values are in the normal range. In the 23 root replacements, early annulus diameter was within the normal range, but late Z values were larger than normal (p < 0.02). Intraaortic implant annulus diameter increased proportionally to somatic growth, but the sinotubular junction, which was small, remained small but increased toward normal. In the root replacements, the annulus increased in diameter and became dilated. The sinotubular junction, which was small early, increased and was within the normal range late. Lower operative risk and valve durability without failure suggest improved results with inclusion cylinder technique.(ABSTRACT TRUNCATED AT 250 WORDS)
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