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Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
12:18

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)

Published on: February 9, 2011

Clinical risk factors for methicillin-resistant Staphylococcus aureus bacteriuria in a skilled-care nursing home

P P Coll1, B F Crabtree, P J O'Connor

  • 1Department of Family Medicine, University of Connecticut.

Archives of Family Medicine
|April 1, 1994
PubMed
Abstract

Insights

Urinary catheter use and prior antibiotic exposure are key risk factors for methicillin-resistant Staphylococcus aureus (MRSA) bacteriuria in nursing homes. These findings highlight potential control measures for MRSA spread in long-term care settings.

Area of Science:

  • Infectious Diseases
  • Gerontology
  • Healthcare Epidemiology

Background:

  • Methicillin-resistant Staphylococcus aureus (MRSA) is increasingly prevalent in nursing home settings.
  • MRSA bacteriuria may serve as a significant reservoir for organism transmission in long-term care facilities.

Purpose of the Study:

  • To identify risk factors associated with methicillin-resistant Staphylococcus aureus (MRSA) bacteriuria.
  • To inform potential control strategies for MRSA in nursing home populations.

Main Methods:

  • A case-control study was conducted in a skilled-care nursing facility.
  • Fifteen residents with MRSA bacteriuria (cases) were compared with 40 randomly selected residents without MRSA bacteriuria (controls).

Main Results:

  • Indwelling urinary catheter use showed a strong association with MRSA bacteriuria (OR, 36).
  • Prior antibiotic use within 6 months (OR, 2.9) and impaired physical function (OR, 5.8) were also significant risk factors.
  • Urinary catheter and antibiotic use remained significant predictors after controlling for physical function.

Conclusions:

  • Urinary catheter use and antibiotic exposure are significant risk factors for MRSA bacteriuria in nursing home residents.
  • Conservative use of indwelling urinary catheters and broad-spectrum antibiotics warrants investigation as MRSA control measures.
  • Reducing MRSA spread in nursing homes requires targeted interventions focusing on these identified risk factors.

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