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[Primary spinal intramedullary malignant lymphoma: case report]

K Nakao¹, S Waga, H Sakaida

¹Department of Neurosurgery, Mie University School of Medicine.

No Shinkei Geka. Neurological Surgery

|June 1, 1994

Summary

This case study details a rare instance of primary spinal intramedullary malignant lymphoma in a 48-year-old man. Despite initial treatment, the lymphoma recurred in the brain, leading to a fatal outcome.

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Area of Science:

Neurology
Oncology
Pathology

Background:

Primary spinal intramedullary malignant lymphoma is a rare condition.
Central nervous system lymphomas are increasingly recognized.

Observation:

A 48-year-old male presented with progressive paraplegia and urinary retention.
MRI revealed a thoracic spinal cord mass, initially suspected as a tumor.
Biopsy confirmed diffuse medium-sized cell malignant lymphoma.

Findings:

The patient was diagnosed with primary spinal intramedullary malignant lymphoma after excluding other sites.
Post-treatment, the spinal lesion resolved, but brain metastases appeared.
The patient succumbed to the disease 15 months after symptom onset.

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Implications:

This case highlights the importance of considering lymphoma in the differential diagnosis of spinal cord tumors.
Further research into effective chemoradiotherapy regimens for primary spinal lymphoma is warranted.
Early diagnosis and comprehensive treatment strategies are crucial for improving patient outcomes.