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Minocycline-related lupus
P A Byrne1, B D Williams, M H Pritchard
1Department of Rheumatology, University Hospital of Wales, Cardiff.
British Journal of Rheumatology
|July 1, 1994
Summary
Minocycline use may trigger a lupus-like syndrome in susceptible individuals. Symptoms like joint pain and positive antinuclear factor resolved after discontinuing minocycline, with recurrence upon re-challenge.
Area of Science:
- Rheumatology
- Dermatology
- Clinical Pharmacology
Background:
- Minocycline, a tetracycline antibiotic, is widely used for various conditions.
- Drug-induced lupus erythematosus (DILE) is a recognized adverse effect of certain medications.
- Prolonged minocycline therapy has been anecdotally linked to lupus-like symptoms.