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Updated: Aug 11, 2026

Protocol for Long Duration Whole Body Hyperthermia in Mice
Published on: August 25, 2012
A new technological approach to radiant heat whole body hyperthermia
H I Robins1, J P Woods, C L Schmitt
1K4/666 Clinical Science Center, University of Wisconsin Comprehensive Cancer Center, Madison 53792.
Abstract:
A new methodology for administering radiant heat whole body hyperthermia (WBH) in humans is described. The technology utilized circulates hot water in a cylinder constructed from copper tubing; the design incorporates a counter current distribution system to maintain thermal constancy. The tubing is coated with a temperature resistant high emissivity finish. Other features include a humidification system to eliminate evaporative heat losses. Data accrued from initial evaluation of this apparatus with a canine model shows that there was no detectable WBH-related hematological, biochemical or physiological toxicity. The perceived advantages of this WBH-system are discussed.
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