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Acute tubular necrosis after interleukin-2 therapy
1Department of Internal Medicine, Texas Tech University Medical Center, Lubbock 79430.
Immunotherapy with interferon and interleukin-2 is being increasingly used in the treatment of metastatic renal cell cancer. A case is presented in which interleukin-2 (IL2) therapy was complicated by renal tubular necrosis. Renal function returned to normal following aggressive fluid replacement and use of dopamine and cautious diuresis.
Immunotherapy with interferon and interleukin-2 is being increasingly used in the treatment of metastatic renal cell cancer. A case is presented in which interleukin-2 (IL2) therapy was complicated by renal tubular necrosis. Renal function returned to normal following aggressive fluid replacement and use of dopamine and cautious diuresis.