[The interrelation of interhemispheric functional brain asymmetry and the morphofunctional asymmetries of the female reproductive system in in its comparative evolutionary aspect]

In experiments carried out in female rats it has been established that there is a connection between morphological asymmetry of uterine horns and adnexa and orientation of encephalic interhemispheric asymmetry (EIHA). Unilateral adnexectomy and ablation of one of the uterine horns resulted in modifications of EIHA, which increased during pregnancy in the remaining horn. Comparative analysis of experimental results and the data obtained during examination of pregnant women (such as interconnections of the placentation side with gestational dominant and initial orientation of the lateral phenotype) suggests an important role of asymmetry of the visceral part of female reproductive system in the formation of EIHA in onto- and phylogenesis. Possible mechanisms of self-organization of the polar functional systems are discussed under evolutionary aspect.