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[The antibacterial effects of homologous interferons in an experimental staphylococcal infection]

I V Fil'chakov, F V Fil'chakov, V K Ivanenko

    Mikrobiolohichnyi Zhurnal (Kiev, Ukraine : 1993)
    |November 1, 1993
    PubMed

    Homologous interferons (IF) of the 1st and 2nd types are studied for their effect on the course of experimental staphylococcal infection. A model of intracutaneous infection of animals is used. Survival of mice, dynamics of the agent elimination from the organism, functional activity of phagocytes in dynamics of the infectious process during IF administration are studied. Only preparations of natural IF are found to possess a protective effect. The recombinant gamma-IF does not prevents from the mouse death and exerts no effect on the dynamics of elimination of agents from the organism.

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