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Rapid determination of antifungal activity by flow cytometry
L Green1, B Petersen, L Steimel
1Lilly Research Laboratories, Eli Lilly and Co., Indianapolis, Indiana 46202.
Journal of Clinical Microbiology
|April 1, 1994
Abstract:
We have developed a rapid assay of antifungal activity which utilizes flow cytometry to detect accumulation of a vital dye in drug-damaged fungal cells. Results of these studies suggest that flow cytometry may provide an improved, rapid method for determining and comparing the antifungal activities of compounds with differing modes of action.